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Find 5 Star Hotels in South San Francisco, CA from $127

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May 14 - May 15
Tomorrow
May 15 - May 16
This weekend
May 17 - May 19
Next weekend
May 24 - May 26

Compare South San Francisco 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Property amenity
Palace Hotel, a Luxury Collection Hotel, San Francisco
5.0 star property
9.0 out of 10, Wonderful, (1000)
"Excellent accommodations. Love the hotel, beautiful and classic. Great stay. Love Lidia so sweet and helpful. I adore the pool!"
The price is $233
$272 total
includes taxes & fees
Jun 8 - Jun 9
Palace Hotel, a Luxury Collection Hotel, San Francisco
Rooftop terrace
Four Seasons Hotel San Francisco at Embarcadero
5.0 star property
9.4 out of 10, Exceptional, (994)
"Top notch service, clean and very comfortable room with a stunning view. "
The price is $415
$484 total
includes taxes & fees
May 23 - May 24
Four Seasons Hotel San Francisco at Embarcadero
Terrace/patio
Fairmont San Francisco
5.0 star property
8.6 out of 10, Excellent, (1006)
"awesomness"
The price is $248
$330 total
includes taxes & fees
May 19 - May 20
Fairmont San Francisco
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City view
Taj Campton Place
5.0 star property
9.2 out of 10, Wonderful, (1000)
"Excellent Customer Service A "
The price is $168
$231 total
includes taxes & fees
May 26 - May 27
Taj Campton Place
Gift shop
1 Hotel San Francisco
5.0 star property
9.2 out of 10, Wonderful, (222)
"Loved the hospitality of the staff. "
The price is $319
$425 total
includes taxes & fees
May 27 - May 28
1 Hotel San Francisco
Exterior
Claremont Club & Spa - A Fairmont Hotel
5.0 star property
8.8 out of 10, Excellent, (1000)
"Beautiful and well maintained property. Rooms were clean and comfortable. "
The price is $263
$358 total
includes taxes & fees
May 26 - May 27
Claremont Club & Spa - A Fairmont Hotel
Club Suite, 1 Bedroom (San Francisco Suite) | 1 bedroom, Frette Italian sheets, premium bedding, in-room safe
The Ritz-Carlton, San Francisco
5.0 star property
9.2 out of 10, Wonderful, (1000)
"Wow! Wonderful experience. Service was top notch. "
The price is $354
$414 total
includes taxes & fees
May 26 - May 27
The Ritz-Carlton, San Francisco
Terrace/patio
Four Seasons Hotel San Francisco
5.0 star property
9.4 out of 10, Exceptional, (899)
"Everything was great, I mean, it’s the Four seasons! The only part that wasn’t so great was finding out that the pool wasn’t available for kids under 15. It makes sense as it’s part of Equinox, but I didnt see this in the details about the property when booking. "
The price is $415
$484 total
includes taxes & fees
May 25 - May 26
Four Seasons Hotel San Francisco
Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
Four Seasons Hotel Silicon Valley at East Palo Alto
5.0 star property
9.4 out of 10, Exceptional, (543)
"Great "
The price is $316
$359 total
includes taxes & fees
May 25 - May 26
Four Seasons Hotel Silicon Valley at East Palo Alto
Exterior
The St. Regis San Francisco
5.0 star property
9.4 out of 10, Exceptional, (604)
"Classic hotel"
The price is $441
$514 total
includes taxes & fees
May 18 - May 19
The St. Regis San Francisco
Couples treatment rooms, sauna, spa tub, body treatments, hydrotherapy
Rosewood Sand Hill
5.0 star property
9.4 out of 10, Exceptional, (198)
"Very nice property. Service is excellent "
The price is $1,040
$1,235 total
includes taxes & fees
May 18 - May 19
Rosewood Sand Hill
Egyptian cotton sheets, premium bedding, down comforters, in-room safe
The Ritz-Carlton, Half Moon Bay
5.0 star property
9.0 out of 10, Wonderful, (583)
"The grounds are beautiful and plenty of trails. The dining, shops, and activities around the resort are limited. A rental car is a must when staying at the hotel any length of time."
The price is $769
$970 total
includes taxes & fees
May 29 - May 30
The Ritz-Carlton, Half Moon Bay
Meeting facility
Nobu Hotel Palo Alto
5.0 star property
9.2 out of 10, Wonderful, (348)
"Nobu is a truly lovely hotel. We Particularly loved the Zen Garden, and of course the fabulous restaurant. Our only difficulty was with understanding the lighting and blinds system in our room, which was a bit complicated."
The price is $395
$457 total
includes taxes & fees
May 17 - May 18
Nobu Hotel Palo Alto
City view
Hotel Drisco
5.0 star property
9.8 out of 10, Exceptional, (393)
"Check in was flawless. Very accommodating. Room is very comfortable with top quality clean bedding! "
The price is $521
$601 total
includes taxes & fees
May 28 - May 29
Hotel Drisco
Front of property
Mansion on Sutter
5.0 star property
9.4 out of 10, Exceptional, (149)
"Very beautiful and unique hotel, but most notable was the very friendly staff especially Amanda, she made sure we had everything we needed at all times, showed us where everything was and made sure to ask if we needed anything every time she saw us in the lobby. I cannot thank Amanda enough for making our stay comfortable and memorable. The Hotel was everything we had hoped for. I would definitely stay there again. "
The price is $261
$332 total
includes taxes & fees
May 19 - May 20
Mansion on Sutter
Exterior
Fairmont Heritage Place, Ghirardelli Square
5.0 star property
9.4 out of 10, Exceptional, (347)
"Great place"
The price is $955
$1,113 total
includes taxes & fees
May 26 - May 27
Fairmont Heritage Place, Ghirardelli Square
Terrace/patio
Dimond Abode Vacation Rental 3428
5.0 star property
10.0 out of 10, Exceptional, (3)
"Wonderful place to stay! Host was great and the place was clean. Nice neighborhood, safe, and right near a good gas station. Will definitely stay next time I go back to Oakland."
Dimond Abode Vacation Rental 3428

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in South San Francisco.
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

2500 Mason St, San Francisco, CA
The price is $133 per night from May 21 to May 22
$133
$189 total
includes taxes & fees
May 21 - May 22
8.6/10 Excellent! (6,162 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in South San Francisco?
The St. Regis San Francisco, Four Seasons Hotel San Francisco and Mansion on Sutter are among the best 5-star hotels in South San Francisco, according to our traveler reviews. These upscale hotels rate highly for things like their location, conveniences and guest services. Pick your favorite and experience the best of everything.
How much does it cost to stay in a 5-star hotel in South San Francisco?
The amount you pay for a 5-star hotel in South San Francisco depends on things such as when you plan to go and the length of your break. Our insider tip for bagging the best deal? Use our pricing filters to compare the available hotels for your chosen dates.

  • Search for the lowest price per night from $127

What makes a hotel 5 stars in South San Francisco?
In South San Francisco, a hotel must provide a certain number of upscale amenities to be designated 5 stars. These may include on-site gyms, saunas and spas, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding standard of service. You can look forward to things like concierge services, in-room massages and nightly turn-down services. Some may also offer thoughtful touches like welcome gifts.
Are there any 5-star all-inclusive resorts in South San Francisco?
Find an indulgent escape that includes your lodging, meals, drinks and entertainment in South San Francisco with the help of Expedia’s filter tool. Search for hotels with a 5-star rating and select the “All inclusive” filter. Make sure you check what’s included in the price. This way, you’re ready to take advantage of the many perks on offer from the moment you arrive.
What are the top 5-star spa hotels in South San Francisco?
Four Seasons Hotel San Francisco combines plush accommodations with blissful wellness therapies and experiences. Choose from a menu of facials, massages and more at this well-known 5-star spa retreat in South San Francisco.
Are there any 5-star vacation rentals in South San Francisco?
Our site doesn’t have any 5-star vacation rentals in South San Francisco. However, you will still find a few top-rated options where the only thing on your agenda will be to relax and have fun. See what’s available by searching through our vacation rentals in South San Francisco.