Find hotels in Mission Valley, San Diego from $98
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Discover 8,411 Mission Valley hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.
Wyndham San Diego Bayside
Wyndham San Diego Bayside
8.2 out of 10, Very Good, (5922)
The price is $152
$171 total
includes taxes & fees
May 27 - May 28
Paradise Point Resort & Spa
Paradise Point Resort & Spa
8.4 out of 10, Very Good, (1831)
The price is $220
$293 total
includes taxes & fees
May 27 - May 28
The Dana on Mission Bay
The Dana on Mission Bay
8.6 out of 10, Excellent, (2432)
The price is $179
$202 total
includes taxes & fees
May 14 - May 15
Save an average of 15% on thousands of hotels when you're signed in
Omni San Diego Hotel
Omni San Diego Hotel
9.0 out of 10, Wonderful, (1907)
The price is $209
$269 total
includes taxes & fees
May 15 - May 16
Hilton San Diego Bayfront
Hilton San Diego Bayfront
8.4 out of 10, Very Good, (1490)
The price is $155
$223 total
includes taxes & fees
May 28 - May 29
DoubleTree by Hilton San Diego - Del Mar
DoubleTree by Hilton San Diego - Del Mar
7.4 out of 10, Good, (1039)
The price is $127
$142 total
includes taxes & fees
May 27 - May 28
Palihotel San Diego
Palihotel San Diego
8.8 out of 10, Excellent, (503)
The price is $110
$152 total
includes taxes & fees
May 27 - May 28
Hotel Republic San Diego, Autograph Collection
Hotel Republic San Diego, Autograph Collection
9.0 out of 10, Wonderful, (1323)
The price is $170
$217 total
includes taxes & fees
May 27 - May 28
Gaslamp Plaza Suites
Gaslamp Plaza Suites
8.8 out of 10, Excellent, (1009)
The price is $106
$118 total
includes taxes & fees
May 27 - May 28
Catamaran Resort and Spa
Catamaran Resort and Spa
7.8 out of 10, Good, (1118)
The price is $219
$291 total
includes taxes & fees
May 14 - May 15
La Jolla Shores Hotel
La Jolla Shores Hotel
8.8 out of 10, Excellent, (1275)
The price is $343
$423 total
includes taxes & fees
Jun 5 - Jun 6
Loews Coronado Bay Resort
Loews Coronado Bay Resort
8.6 out of 10, Excellent, (1060)
The price is $219
$289 total
includes taxes & fees
May 27 - May 28
Pendry San Diego
Pendry San Diego
9.2 out of 10, Wonderful, (1007)
The price is $269
$353 total
includes taxes & fees
May 27 - May 28
Kona Kai San Diego
Kona Kai San Diego
8.4 out of 10, Very Good, (940)
The price is $229
$309 total
includes taxes & fees
May 28 - May 29
Holiday Inn Express San Diego Downtown, an IHG Hotel
Holiday Inn Express San Diego Downtown, an IHG Hotel
8.2 out of 10, Very Good, (1011)
The price is $144
$162 total
includes taxes & fees
May 27 - May 28
Handlery Hotel
Handlery Hotel
7.8 out of 10, Good, (1569)
The price is $128
$145 total
includes taxes & fees
May 27 - May 28
Sheraton Mission Valley San Diego Hotel
Sheraton Mission Valley San Diego Hotel
8.4 out of 10, Very Good, (1107)
The price is $134
$151 total
includes taxes & fees
May 27 - May 28
Lamplighter Inn & Suites at SDSU
Lamplighter Inn & Suites at SDSU
8.8 out of 10, Excellent, (1014)
The price is $175
$193 total
includes taxes & fees
May 14 - May 15
Springhill Suites San Diego Downtown/Bayfront
Springhill Suites San Diego Downtown/Bayfront
9.2 out of 10, Wonderful, (1001)
The price is $208
$235 total
includes taxes & fees
May 27 - May 28
Four Points by Sheraton San Diego Downtown Little Italy
Four Points by Sheraton San Diego Downtown Little Italy
7.0 out of 10, Good, (1001)
The price is $159
$179 total
includes taxes & fees
May 15 - May 16
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Mission Valley
Where to stay in Mission Valley
Hotels in top San Diego neighborhoods Learn more about Mission Valley
Downtown San Diego
2 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)
From historic streets, waterfront parks and baseball, to performing arts venues, nightlife zones and art and maritime museums, this is the cultural hub of San Diego.
Recent reviews of Mission Valley hotels
Recent reviews of Mission Valley hotels
5/5 Excellent
""The staff was incredibly welcoming and helpful. I would definitely come back!""
A verified traveler stayed at Legacy Resort Hotel & Spa
Posted 14 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in top San Diego neighborhoods
- Downtown San Diego Hotels
- Mission Beach Hotels
- Pacific Beach Hotels
- Gaslamp Quarter Hotels
- Point Loma Hotels
- Ocean Beach Hotels
- Mission Valley Hotels
- Old Town San Diego Hotels
- Central Mission Beach Hotels
- Little Italy Hotels
- South Mission Beach Hotels
- North Pacific Beach Hotels
- Carmel Valley Hotels
- Hillcrest Hotels
- Linda Vista Hotels
- Crown Point Hotels
- Clairemont Hotels
- North Park Hotels
- University City Hotels
- Mid-City Hotels
Hotels near popular San Diego Attractions
- Hotels near Hotel Circle
- Hotels near Snapdragon Stadium
- Hotels near Fashion Valley Mall
- Hotels near Mission Valley Mall
- Hotels near Riverwalk Golf Club
- Hotels near San Diego Zoo
- Hotels near Mission Bay
- Hotels near San Diego Convention Center
- Hotels near Mission Beach
- Hotels near San Ysidro Border Crossing
More Hotel Options in Mission Valley
- Beach Hotels (36)
- Business Hotels (38)
- Cheap Hotels (26)
- Family Hotels (34)
- Golf Hotels (36)
- Historic Hotels (38)
- Hotel Wedding Venues (14)
- Hotel with a Concierge (15)
- Hotels & Resorts for Couples (27)
- Hotels with Air Conditioning (33)
- Hotels with Balconies (20)
- Hotels with Bars (27)
- Hotels with Connecting Rooms (17)
- Hotels with Free Breakfast (25)
- Hotels with Free Parking (26)
- Hotels with Free Wifi (30)
- Hotels with Hot Tubs (28)
- Hotels with Laundry Facilities (31)
- Hotels with Restaurants (33)
- Hotels with Room Service (19)
- Hotels with Suites (12)
- Hotels with a Gym (27)
- Hotels with a Pool (33)
- Hotels with a View (25)
- Hotels with an Outdoor Pool (33)
- Hotels with smoking rooms (11)
- Luxury Hotels (23)
- Non-Smoking Hotels (24)
- Pet-friendly Hotels (21)
- Quiet Resorts & Hotels (10)
- Resorts & Hotels with Spas (29)
- Romantic Hotels (22)
Hotels Close to Nearby Airports
More Popular Hotels in San Diego
- Paradise Point Resort & Spa
- Hilton San Diego Bayfront
- Manchester Grand Hyatt San Diego
- San Diego Mission Bay Resort
- Sheraton San Diego Hotel and Marina
- Bahia Resort Hotel
- Hyatt Regency Mission Bay Spa and Marina
- Loews Coronado Bay Resort
- The Dana on Mission Bay
- Wyndham Garden San Diego Near SeaWorld
- Hard Rock Hotel San Diego
- Inn By The Sea La Jolla