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Discover 11,947 Matlacha Isles hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
Exterior
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
8.6 out of 10, Excellent, 1,003 reviews
"Excellent service "
The price is $107
$119 total
includes taxes & fees
Jun 8 - Jun 9
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
Angler's Inn
Dock
Angler's Inn
2.5 star property
9.4 out of 10, Exceptional, 288 reviews
"Excellent location and room! We enjoyed sitting out on the deck/dock in the morning with our tea watching an osprey family nearby. We had everything in our room to be comfortable and to make our own meals or a short walk for area restaurants. "
The price is $165
$273 total
includes taxes & fees
Jun 2 - Jun 3
Angler's Inn
Waterfront Cape Coral Oasis w/ Boat Dock & Lanai!
Fridge, microwave, stovetop, dishwasher
Waterfront Cape Coral Oasis w/ Boat Dock & Lanai!
9.8 out of 10, Exceptional, 37 reviews
"Quiet neighborhood, Needed private quiet space to unwind and this was perfect."
Waterfront Cape Coral Oasis w/ Boat Dock & Lanai!
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Brand new beautiful Guest House
Exterior
Brand new beautiful Guest House
9.4 out of 10, Exceptional, 11 reviews
"Tiny hotel room, ideal for our purpose! Clean and comfortable."
The price is $105
$205 total
includes taxes & fees
Jun 2 - Jun 3
Brand new beautiful Guest House
New Salt System Pool, Recently remodeled, large Canal, Beach & Bikes
A heated pool
New Salt System Pool, Recently remodeled, large Canal, Beach & Bikes
9.8 out of 10, Exceptional, 111 reviews
"The property was very clean, also enjoyed the pool and the dock outback. I fished and caught multiple different types of fish in the canal behind the house. The house comes with fishing pools but you will need to buy reels if you want to fish, also the bikes come with the house and they are very fun to ride. I would come back to this house and recommend it to others!"
The price is $169
$458 total
includes taxes & fees
Jun 30 - Jul 1
New Salt System Pool, Recently remodeled, large Canal, Beach & Bikes
Newly renovated condominium in the heart of downtown Cape Coral
Beach
Newly renovated condominium in the heart of downtown Cape Coral
10.0 out of 10, Exceptional, 55 reviews
"Very comfortable and clean. Had everything we needed. Great location!"
Newly renovated condominium in the heart of downtown Cape Coral
Paradise Luxury Apartment
Property grounds
Paradise Luxury Apartment
9.6 out of 10, Exceptional, 46 reviews
"We needed an economical place to stay while renovating our home and this was just perfect for us."
Paradise Luxury Apartment
Gulf Access Waterfront Large One or Two Bedroom In Law Suite
Property grounds
Gulf Access Waterfront Large One or Two Bedroom In Law Suite
10.0 out of 10, Exceptional, 29 reviews
"Everything was great. Place was clean, decorated nicely, very quiet neighborhood and a Great lanai!"
Gulf Access Waterfront Large One or Two Bedroom In Law Suite
Beautiful Waterfront with Heated Pool - Extra wide canal - pet friendly
Fridge, microwave, oven, stovetop
Beautiful Waterfront with Heated Pool - Extra wide canal - pet friendly
9.4 out of 10, Exceptional, 138 reviews
"It was a short stay for business over a weekend. It was clean and quiet and the pool was nice. Would stay again."
The price is $179
$471 total
includes taxes & fees
Jun 2 - Jun 3
Beautiful Waterfront with Heated Pool - Extra wide canal - pet friendly
Modern Elegance, Unwind in Style, NEW Heated Pool!
Pool
Modern Elegance, Unwind in Style, NEW Heated Pool!
10.0 out of 10, Exceptional, 11 reviews
"Loved the cleanliness of the home."
The price is $114
$489 total
includes taxes & fees
Jun 27 - Jun 28
Modern Elegance, Unwind in Style, NEW Heated Pool!
King Bed Suite | Renovated 11-22 | Waterfront + Pool | Modern | Near Downtown
Property grounds
King Bed Suite | Renovated 11-22 | Waterfront + Pool | Modern | Near Downtown
9.4 out of 10, Exceptional, 16 reviews
"Great communication with owner. Owner very helpful with whatever I needed. Very modern updated accommodations. King bed very comfy !"
The price is $120
$340 total
includes taxes & fees
Jun 3 - Jun 4
King Bed Suite | Renovated 11-22 | Waterfront + Pool | Modern | Near Downtown
Waterfront Retreat
Fridge, microwave, oven, stovetop
Waterfront Retreat
9.6 out of 10, Exceptional, 15 reviews
"We had an amazing time staying here. The house was incredibly welcoming! Merecedes made the whole process so easy and seamless. A nice perk is being able to catch fish right off the dock! We loved it!!!"
Waterfront Retreat
Cape Coral Oasis -2 mins to downtown Cape Coral
Beach
Cape Coral Oasis -2 mins to downtown Cape Coral
7.6 out of 10, Good, 9 reviews
"It was nice"
The price is $125
$321 total
includes taxes & fees
Jul 1 - Jul 2
Cape Coral Oasis -2 mins to downtown Cape Coral
Pet-friendly Fort Myers Home w/ Heated Pool!
Interior
Pet-friendly Fort Myers Home w/ Heated Pool!
3.0 star property
10.0 out of 10, Exceptional, 3 reviews
"Was everything as advertised. Also clean, and no issues with anything at all..Would love to go back"
Pet-friendly Fort Myers Home w/ Heated Pool!
'BEST BUY' Affordable & Beautiful Waterfront Condo w/Sunbathing Deck
Property grounds
'BEST BUY' Affordable & Beautiful Waterfront Condo w/Sunbathing Deck
10.0 out of 10, Exceptional, 31 reviews
"A nice, well equipped unit with great views of the canal."
'BEST BUY' Affordable & Beautiful Waterfront Condo w/Sunbathing Deck
Cape Coral Vacation Rentals - Villa Santa Rosa Cape Coral
Exterior
Cape Coral Vacation Rentals - Villa Santa Rosa Cape Coral
9.2 out of 10, Wonderful, 13 reviews
"House was remodeled nicely love all the spaces especially out by the dock"
Cape Coral Vacation Rentals - Villa Santa Rosa Cape Coral
Feel Like Home in Cape Coral
Property grounds
Feel Like Home in Cape Coral
9.4 out of 10, Exceptional, 6 reviews
"The home was nice. As a family with alot od allergies there were like 8 or more plug-ins and the smell of the house was overbearing. We had to unplug them all and open the windows and doors for 2 hrs in 95*+ heat and it was hot. If you are susceptible to smells ask owner to have them unpluged when cleaning crew is there before you arrive. Also Just FYI if you have dogs the backyard fence is damaged and dogs can get out. But the over-all stay was nice"
Feel Like Home in Cape Coral
Canalfront Cape Coral Escape: Lanai w/ Pool!
TV, table tennis
Canalfront Cape Coral Escape: Lanai w/ Pool!
7.6 out of 10, Good, 5 reviews
"Very nice property to enjoy with the family."
Canalfront Cape Coral Escape: Lanai w/ Pool!
Bright & Airy 2bed 2bath home near downtown.
Pool
Bright & Airy 2bed 2bath home near downtown.
9.8 out of 10, Exceptional, 31 reviews
"The unit was bright and clean. It came with a stocked kitchen with staples and many appliances and kitchen utensils. It felt like we were visiting the home of a friend. The medicine cabinets had things you might need. Coffee, creamer and sweetener were provided. There were games in one closet. And there are two cute ground owls who live in a hole in front of the neighbors mailbox, plus a cottontail rabbit that stopped by one morning. Toiletries were provided. There was a wagon with beach chairs....
The price is $85
$232 total
includes taxes & fees
Jun 4 - Jun 5
Bright & Airy 2bed 2bath home near downtown.
Sunny Cape Coral Home w/ Private Pool & Lanai
Interior
Sunny Cape Coral Home w/ Private Pool & Lanai
3.5 star property
10.0 out of 10, Exceptional, 2 reviews
"This place has charm. Its clean and well kept. My 2nd time staying here."
Sunny Cape Coral Home w/ Private Pool & Lanai
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See all available properties in Matlacha Isles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Matlacha Isles

Hotels in top Cape Coral neighborhoods Learn more about Matlacha Isles
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Pelican

1 out of top 10 points of interest in this area
4.5/5(46 area reviews)

If you're spending some time in Pelican, Tarpon Point and Rotary Park Environmental Center are top sights worth seeing.

Find hotels in Pelican

Matlacha Isles Travel Info

Number of reviews
1,768
Location
Cape Coral, United States of America
Similar neighborhoods
Hancock, Matlacha Isles-Matlacha Shores and Burnt Store
Accommodation
11,947 hotels
Known landmarks
Royal Tee Golf Club
Hotels with bars
Beautiful 3 bed/2 bath home in one of the best locations in Cape Coral, The Blue Lagoon With Heated Pool /on the Canal With NEW Boat Lift and Dock and Villa Coral Escape - Treat Yourself to the Perfect Tropical Getaway
Lowest price
$85
Highest price
$179

Frequently asked questions

What is Matlacha Isles like?

Travelers will be sure to find plenty to entertain them in Cape Coral's Matlacha Isles neighborhood.

Where is the best place to stay in Matlacha Isles?

For your stay in Matlacha Isles, The Blue Lagoon with heated pool /on the Canal with NEW Boat Lift and Dock is one of the top choices based on our traveler data. Other good options for your stay in the area include The Perfect Day in Matlacha! Direct Gulf Access! and NEW! Matlacha Isles Oasis w/ Gulf Access & Pool!.

How many hotels will I be able to find in the Matlacha Isles area?

When you want to kick up your feet after a day of exploring the sights in Cape Coral, you can choose from 14 Expedia hotels and other accommodations in Matlacha Isles.

If I need to cancel my hotel reservation in Matlacha Isles, will I receive a refund?

Yes, you'll find most hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best deals available in Matlacha Isles.

Where can I learn more about changing or cancelling my trip to Matlacha Isles?

To find more details about changing or cancelling your trip to Matlacha Isles, go to https://www.expedia.com/service/.

What are the top things to see and do in Matlacha Isles?

A few places to visit in the area around Matlacha Isles include Griffen American Center for Haitian Art, Lovegrove Gallery & Gardens, and Royal Tee Golf Club. While you're out sightseeing in Cape Coral, be sure to visit other sights like Little Dead Key or Big Dead Key.

Recent reviews of Matlacha Isles hotels

Sanibel Island Beach Resort

Sanibel Island Beach Resort

5/5 Excellent
"Got a room close to the pool and beach, which was great for the kids!!"
A verified traveler stayed at Sanibel Island Beach Resort
Posted 15 hours ago
Sanibel Island Beach Resort