Find hotels in De Soto, WI from $67

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    one key icon
    Treat yourself
    Save instantly and earn perks with One Key
    today icon
    Change your mind
    Book hotels with free cancellation

Check De Soto hotel prices

Tomorrow night
Next weekend

Filter by

Popular filters
Popular filters
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveler experience
Traveler experience

Compare 283 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Windsor Place Inn
2.0 star property
8.4 out of 10, Very Good, 741 reviews
"Decent room for a decent price. "
The price is $77
$85 total
includes taxes & fees
Jun 2 - Jun 3
Windsor Place Inn
Waterfront Hotel
3.0 star property
9.2 out of 10, Wonderful, 561 reviews
"The breakfast area was very spacious and the breakfast options very plentiful. We had dinner in the patio restaurant which was a real pleasure."
The price is $143
$160 total
includes taxes & fees
Jun 2 - Jun 3
Waterfront Hotel
AmericInn by Wyndham Prairie du Chien
2.0 star property
8.0 out of 10, Very Good, 412 reviews
"Stay was great, we walked Effigy Mounds and Pikes Peak, went to a winery and the fish and cheese shop. Always have a great time in Prairie Du Chien. The best bars! Live music at the Tavern "
The price is $85
$93 total
includes taxes & fees
Jun 2 - Jun 3
AmericInn by Wyndham Prairie du Chien
Save an average of 15% on thousands of hotels when you're signed in
Microtel Inn & Suites by Wyndham Prairie du Chien
2.5 star property
8.4 out of 10, Very Good, 442 reviews
"Great value! Room smells musty, but otherwise nice and clean."
The price is $71
$79 total
includes taxes & fees
Jun 2 - Jun 3
Microtel Inn & Suites by Wyndham Prairie du Chien
Country Inn & Suites by Radisson, Prairie du Chien, WI
3.0 star property
8.4 out of 10, Very Good, 774 reviews
"Our stay was great. Staff was great. The only complaint I have was the hotel was dated and the beds and pillows were junk. It was to be expected with a hotel geared towards families with children. "
The price is $80
$89 total
includes taxes & fees
Jun 2 - Jun 3
Country Inn & Suites by Radisson, Prairie du Chien, WI
Quality Inn & Suites
2.5 star property
8.0 out of 10, Very Good, 253 reviews
"A good hotel for the price. "
The price is $67
$74 total
includes taxes & fees
Jun 2 - Jun 3
Quality Inn & Suites
Cobblestone Inn & Suites - Marquette/Prairie du Chien
2.5 star property
9.0 out of 10, Wonderful, 781 reviews
"Beds are extremely comfortable. Very clean rooms and clean hotel. Staff was exceptionally courteous. Five stars. "
The price is $110
$123 total
includes taxes & fees
Jun 2 - Jun 3
Cobblestone Inn & Suites - Marquette/Prairie du Chien
Scenic Valley Motel
2.0 star property
8.4 out of 10, Very Good, 35 reviews
"Very quaint and clean and nice little motel. We didn’t spend much time there but the beds were comfy and the showers were hot. People upstairs were kind of noisy but we dealt and mostly ignored it. Will definitely be back tho. "
The price is $90
$100 total
includes taxes & fees
Jun 2 - Jun 3
Scenic Valley Motel
Trickling Waters Retreat
3.0 star property
9.8 out of 10, Exceptional, 216 reviews
"All the birds, squirrels, chipmunks, & the fish pond made a very peaceful setting to spend time outside in and enjoy God's creation."
The price is $79
$88 total
includes taxes & fees
Jun 2 - Jun 3
Trickling Waters Retreat
Walnut Ridge Cabin w/ Hot Tub
9.6 out of 10, Exceptional, 11 reviews
"Great back yard. Good for dogs. Near nice hiking trails. Cant stand up in loft and no electricity up there."
The price is $95
$250 total
includes taxes & fees
Jun 3 - Jun 4
Walnut Ridge Cabin w/ Hot Tub
Sunset Lodge w/ Hot Tub & Pool... 9 Bedrooms
9.6 out of 10, Exceptional, 4 reviews
"House was easy to get to, beautiful views, quiet and serene. Plenty of room!!!"
The price is $95
$337 total
includes taxes & fees
Jun 5 - Jun 6
Sunset Lodge w/ Hot Tub & Pool... 9 Bedrooms
House on the Hill within walking distance of shopping and marina!
10.0 out of 10, Exceptional, 24 reviews
"A weekend in McGregor IA to attend a family funeral. Our hosts were amazing from the time we booked till we left to check in w/us on our accommodations. The property is a beautiful home w/ all new amenities plus dog friendly. We had access to a full backyard for our dog plus able to grill out & sit on a private balcony to enjoy meals & overlook downtown McGregor! We highly recommend this property. Super clean & has everything you need to feel like you are @ home. Thank you to our hosts. A true...
House on the Hill within walking distance of shopping and marina!
Thornwood Cottage is the perfect little get away
10.0 out of 10, Exceptional, 88 reviews
"Although this cabin was smaller than anticipated, it fully lived up to the expression of "small but mighty"! My husband and I had a few nights of a mini honeymoon here to get away from life stressors, anyone we know, and disconnect from our phones to settle into marriage- this cabin was exactly what we were looking for and more! Visiting the small businesses in both towns of Lansing and McGregor was a blast- I highly suggest chatting with the locals! We hope to stay here again soon to be able...
Thornwood Cottage is the perfect little get away
Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!
9.6 out of 10, Exceptional, 44 reviews
"Absolutely beautiful, quiet farm location. Lodgings are scrupulously clean and beautifully decorated. The bathroom was bigger than my bedroom! Lovely host gave us a quick tour of the property, and we met a 2-week old filly. We will stay here again!"
The price is $99
$180 total
includes taxes & fees
Jun 9 - Jun 10
Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!
Beaver Cabin
10.0 out of 10, Exceptional, 7 reviews
"Very comfortable and clean place. Convenient location to the downtown area. Enjoyed the stay very much."
The price is $145
$280 total
includes taxes & fees
Jun 5 - Jun 6
Beaver Cabin
Cozy Log Cabin next to the Mississippi River
9.6 out of 10, Exceptional, 61 reviews
"This cabin and property were a perfect choice for our fishing getaway. We were a little concerned about the available space for 4 large adults in the cabin as well as two boats and two trucks, but everything turned out great. Cabin ended up being perfect. Location to the boat ramp was really good and we were able to fit our boats and trucks at the location. We would have preferred a bit more space for parking, but the road wasnt very busy and it all worked out just fine. Cabin is stocked with...
Cozy Log Cabin next to the Mississippi River
Cabin by the River: Visited by Treehouse Masters!
9.2 out of 10, Wonderful, 50 reviews
"We originally thought we were renting the entire cabin but quickly realized we were renting just half of the cabin upon arriving. I will read future VRBO descriptions much more carefully next time. My mistake! It was a very nice cabin next to a train and road in the middle of God's country (WI). We drove alot and took looks around. It was a great time!! Thank you!! Theresa and Bob"
Cabin by the River: Visited by Treehouse Masters!
Ohio Street Retreat
10.0 out of 10, Exceptional, 26 reviews
"Many listings can seem to over-sell the condition of the property, or the scope of other benefits the property offers to people staying there. Neither of these things happened for me and my wife during our stay here. I believe the description was undersold in the listing, since the property more than exceeded our expectations. Extremely clean, and neat. All listed amenities were present, and those that we accessed were 100% useful. Definitely recommend this location to anyone considering a stay...
The price is $125
$152 total
includes taxes & fees
Jun 6 - Jun 7
Ohio Street Retreat
Just steps to restaurants, shopping, music & the Mississippi River.
9.6 out of 10, Exceptional, 5 reviews
"It’s a cute 3 bedroom apartment. Very comfortable with lots of treats (coffee, popcorn). However, there was a lot of noise into the early morning hours from the bar across the street in the one bedroom with a window facing the street. We stayed a Friday night perhaps it’s quieter during the week."
The price is $200
$318 total
includes taxes & fees
Jun 30 - Jul 1
Just steps to restaurants, shopping, music & the Mississippi River.
2 Bedroom Cabin Fantastic Mississippi River View
10.0 out of 10, Exceptional, 36 reviews
"This was a wonderful property with a wonderful view and wonderful host."
2 Bedroom Cabin Fantastic Mississippi River View
Don't see what you're looking for?
See all available properties in De Soto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

De Soto Travel Info

Number of reviews
4,559
Accommodation
283 hotels
Highest price
$200
Lowest price
$67

Frequently asked questions

What's the best place for a stay in De Soto?

Based on Expedia's traveler preferences, Rustic Hideaway Sleeps 4 HOT TUB is a top place to stay in De Soto. Paradise Point- Sleeps 4 HOT TUB is another good choice for your trip. See all available top hotels, or vacation rentals in De Soto.

What's the top vacation rental that De Soto has to offer?

Majestic View Sleeps 10-HOT TUB: This highly rated vacation home rental in De Soto is located on a river and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a spa tub. See all vacation rentals in De Soto.

If I need to cancel my hotel reservation in De Soto, will I receive a refund?

Yes, the majority of room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.

Where can I learn more about changing or cancelling my trip to De Soto?

For more information about updating your trip to De Soto or cancelling it, go to https://www.expedia.com/service/.

What are some accommodations with pools in De Soto?

Gundersen Hotel & Suites: Hotel located near La Crosse Center. Provides buffet, an indoor pool, and complimentary wired internet access. View all hotels with pools in De Soto.

What is the best accommodation for staying close to La Crosse Municipal Airport (LSE)?

Country Inn & Suites by Radisson, La Crosse, WI is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 1.7 mi (2.8 km) from La Crosse Municipal Airport. Other options near the airport are AmericInn by Wyndham La Crosse Riverfront-Conference Center and Motel 6 La Crosse, WI.

What is staying in De Soto like?

Visitors are sure to enjoy all that De Soto has to offer. In De Soto, there are 24 hotels and other accommodations to choose from. Find out more about De Soto.

What are the top places to visit in De Soto?

A favorite place to visit is Mississippi River. You'll also find Yellow River State Forest and Mount Hosmer Park in the area. Check out what more to see and do in Expedia's De Soto guide.

What's the weather like in De Soto?

The hottest months are usually July and August with an average temp of 68°F, while the coldest months are January and February with an average of 24°F. The snowiest months in De Soto are January, April, March, and February, with each month seeing an average of 9 inches of snowfall.

Recent reviews of De Soto hotels
Expedia verified reviews