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Compare 1,109 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
9.4 out of 10, Exceptional, (608)
The price is $108
$126 total
includes taxes & fees
Jul 4 - Jul 5
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
7.6 out of 10, Good, (1210)
The price is $108
$125 total
includes taxes & fees
Jun 24 - Jun 25
Kahler Grand Hotel
Kahler Grand Hotel
8.2 out of 10, Very Good, (1012)
The price is $139
$161 total
includes taxes & fees
Jun 28 - Jun 29
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Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
9.0 out of 10, Wonderful, (561)
The price is $111
$128 total
includes taxes & fees
Jun 16 - Jun 17
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
7.8 out of 10, Good, (1003)
The price is $91
$105 total
includes taxes & fees
Jun 30 - Jul 1
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
8.8 out of 10, Excellent, (546)
The price is $118
$139 total
includes taxes & fees
Jul 2 - Jul 3
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
8.6 out of 10, Excellent, (1003)
The price is $100
$115 total
includes taxes & fees
Jun 16 - Jun 17
St James Hotel, a Historic Hotel of America
St James Hotel, a Historic Hotel of America
9.2 out of 10, Wonderful, (988)
The price is $161
$184 total
includes taxes & fees
Jun 6 - Jun 7
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
8.0 out of 10, Very Good, (1004)
The price is $67
$77 total
includes taxes & fees
Jun 23 - Jun 24
Motel 6 Mankato, MN
Motel 6 Mankato, MN
9.2 out of 10, Wonderful, (871)
The price is $72
$80 total
includes taxes & fees
Jun 13 - Jun 14
AmericInn by Wyndham Mankato Event Center
AmericInn by Wyndham Mankato Event Center
9.0 out of 10, Wonderful, (1007)
The price is $89
$98 total
includes taxes & fees
Jun 23 - Jun 24
Hampton Inn Rochester-South
Hampton Inn Rochester-South
9.0 out of 10, Wonderful, (1009)
The price is $96
$111 total
includes taxes & fees
Jun 23 - Jun 24
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
8.2 out of 10, Very Good, (395)
The price is $88
$102 total
includes taxes & fees
Jun 9 - Jun 10
Express Suites Riverport Inn & Suites
Express Suites Riverport Inn & Suites
8.6 out of 10, Excellent, (1005)
The price is $110
$123 total
includes taxes & fees
Jun 6 - Jun 7
Residence Inn by Marriott Rochester Mayo Clinic Area South
Residence Inn by Marriott Rochester Mayo Clinic Area South
9.4 out of 10, Exceptional, (86)
The price is $114
$131 total
includes taxes & fees
Jun 22 - Jun 23
Days Inn by Wyndham Winona
Days Inn by Wyndham Winona
7.8 out of 10, Good, (1003)
The price is $70
$78 total
includes taxes & fees
Jun 6 - Jun 7
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
9.0 out of 10, Wonderful, (620)
The price is $118
$136 total
includes taxes & fees
Jun 16 - Jun 17
The Plaza Hotel & Suites Winona
The Plaza Hotel & Suites Winona
9.0 out of 10, Wonderful, (971)
The price is $145
$162 total
includes taxes & fees
Jun 6 - Jun 7
TownePlace Suites by Marriott Rochester Mayo Clinic Area
TownePlace Suites by Marriott Rochester Mayo Clinic Area
9.8 out of 10, Exceptional, (284)
The price is $109
$125 total
includes taxes & fees
Jun 29 - Jun 30
Nichols Inn of Red Wing
Nichols Inn of Red Wing
9.0 out of 10, Wonderful, (666)
The price is $83
$91 total
includes taxes & fees
Jun 6 - Jun 7
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Southern Minnesota
Find the best Southern Minnesota areas and neighborhoods for the activities you enjoy most. Learn more about Southern Minnesota
Downtown Rochester
2 out of top 10 points of interest in this area
4.5/5(250 area reviews)
If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.
More cheap stays in Southern Minnesota
Redwood Lodge
1382 E Bridge St, Redwood Falls, MN
The price is $97 per night from Jun 9 to Jun 10
$97
$119 total
includes taxes & fees
Jun 9 - Jun 10
8.6/10 Excellent! (483 reviews)
Stay near popular Southern Minnesota attractions
Forestville Mystery Cave State Park
4.5/5(10 reviews)
Explore the great outdoors at Forestville Mystery Cave State Park, a lovely green space in Preston. Discover the countryside while you're in the area.
Recent reviews of Southern Minnesota hotelsExpedia verified reviews
5/5 Excellent
"Nice"
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Posted 2 days ago
Hotels in Southern Minnesota Neighborhoods
Stay near popular Southern Minnesota attractions
- Mayo Clinic
- Mayo Clinic Hospital - Saint Marys Campus
- Treasure Island Casino
- Mayo Civic Center
- Minnesota State University
- Lake Pepin
- Apache Mall
- Mayo Clinic Health System Event Center
- Lake Shetek State Park
- Forestville Mystery Cave State Park
- Jackpot Junction Casino
- Winona State University
- Shattuck-St. Mary's School
- Laura Ingalls Wilder Museum
- Olmsted County Fairgrounds
- Root River
- Rochester Recreation Center
- Albert Lea City Arena
- Rochester Community and Technical College
- Carleton College
More Hotel Options in Southern Minnesota
- Business Hotels (126)
- Cheap Hotels (65)
- Family Hotels (153)
- Golf Hotels (129)
- Historic Hotels (109)
- Hotel Wedding Venues (44)
- Hotels & Resorts for Couples (67)
- Hotels with Air Conditioning (178)
- Hotels with Balconies (14)
- Hotels with Bars (70)
- Hotels with Connecting Rooms (60)
- Hotels with Free Breakfast (147)
- Hotels with Free Parking (169)
- Hotels with Free Wifi (176)
- Hotels with Hot Tubs (91)
- Hotels with Laundry Facilities (131)
- Hotels with Restaurants (171)
- Hotels with Room Service (24)
- Hotels with Suites (28)
- Hotels with a Gym (88)
- Hotels with a Pool (114)
- Hotels with a View (16)
- Hotels with an Indoor Pool (103)
- Hotels with an Outdoor Pool (103)
- Hotels with smoking rooms (14)
- Luxury Hotels (50)
- Non-Smoking Hotels (109)
- Pet-friendly Hotels (114)
- Resorts & Hotels with Spas (82)
- Romantic Hotels (14)
- Ski Hotels (29)
- Winery Hotels (14)
Southern Minnesota Hotels by Brand
Other Hotels near Southern Minnesota, Minnesota
- Sioux Falls Hotels
- Bloomington Hotels
- Rochester Hotels
- La Crosse Hotels
- St. Paul Hotels
- Okoboji Hotels
- Stillwater Hotels
- Mankato Hotels
- Decorah Hotels
- Eagan Hotels
- Arnolds Park Hotels
- Red Wing Hotels
- Winona Hotels
- Shakopee Hotels
- Hudson Hotels
- Spirit Lake Hotels
- Prior Lake Hotels
- Woodbury Hotels
- Eden Prairie Hotels
- Onalaska Hotels
More Popular Hotels in Minnesota
- TownePlace Suites by Marriott Rochester Mayo Clinic Area
- Aspen Select
- AmericInn by Wyndham Mankato Event Center
- Brentwood Inn & Suites
- The Plaza Hotel & Suites Winona
- Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
- Country Inn & Suites by Radisson, Albert Lea, MN
- Express Suites Riverport Inn & Suites
- Motel 6 Mankato, MN
- Redwood Lodge
- Ramada by Wyndham Albert Lea
- Super 8 by Wyndham Winona MN
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