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Find hotels in Southeast Missouri, MO from $57

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Check Southeast Missouri hotel prices

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Jun 9 - Jun 10
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Jun 10 - Jun 11
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Jun 14 - Jun 16

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Compare 565 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Auburn Place Hotel And Suites
BBQ/picnic area
Auburn Place Hotel And Suites
2.5 star property
8.8 out of 10, Excellent, 1,005 reviews
"Very relaxing "
The price is $66
$75 total
includes taxes & fees
Jul 8 - Jul 9
Auburn Place Hotel And Suites
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
9.6 out of 10, Exceptional, 1,002 reviews
"Love, love this hotel"
The price is $112
$127 total
includes taxes & fees
Jun 16 - Jun 17
Drury Plaza Hotel Cape Girardeau Conference Center
Pear Tree Inn Cape Girardeau West
Lobby
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, 1,014 reviews
"It was nice helpful staff"
The price is $70
$79 total
includes taxes & fees
Jun 16 - Jun 17
Pear Tree Inn Cape Girardeau West
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Baymont Inn and Suites by Wyndham Farmington, MO
Exterior
Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
8.0 out of 10, Very Good, 634 reviews
"Helpful staff, clean room and bathroom. Basic hotel, with coffee maker in the room and clean comfortable bed. Nice shower and tub, with lots of towels. Quiet area of town with a nice restaurant attached. Would definitely stay here again. Good Price. "
The price is $59
$67 total
includes taxes & fees
Jun 12 - Jun 13
Baymont Inn and Suites by Wyndham Farmington, MO
Pear Tree Inn Cape Girardeau Near the Medical Center
Seasonal outdoor pool
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
9.0 out of 10, Wonderful, 1,005 reviews
"Very friendly, professional and personable staff that we interacted with including front desk, house keeping and and older gentleman wearing a blue uniform."
The price is $63
$71 total
includes taxes & fees
Jul 7 - Jul 8
Pear Tree Inn Cape Girardeau Near the Medical Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 star property
9.6 out of 10, Exceptional, 1,014 reviews
"OK"
The price is $117
$133 total
includes taxes & fees
Jun 16 - Jun 17
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Motel 6 Poplar Bluff, MO
Blackout drapes, free WiFi, bed sheets
Motel 6 Poplar Bluff, MO
2.0 star property
8.0 out of 10, Very Good, 1,006 reviews
"Property needs central air in lobby and hallways. Pretty stuffy place to stay. Room had amazing ac unit stayed cold all day and night. "
The price is $75
$80 total
includes taxes & fees
Jun 17 - Jun 18
Motel 6 Poplar Bluff, MO
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
2.5 star property
8.8 out of 10, Excellent, 386 reviews
"Had late check-in which went smoothly. Room was clean. Staff was attentive at check-in, breakfast and check-out."
The price is $88
$95 total
includes taxes & fees
Jun 13 - Jun 14
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Cape Girardeau
Lobby
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, 789 reviews
"The hotel is located in an area with shopping and restaurants are in walking distance. It is very clean and quiet. "
Drury Inn & Suites Cape Girardeau
Courtyard by Marriott Cape Girardeau Downtown
Lobby
Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
9.6 out of 10, Exceptional, 344 reviews
"Beautiful renovation. "
The price is $118
$134 total
includes taxes & fees
Jun 16 - Jun 17
Courtyard by Marriott Cape Girardeau Downtown
Drury Inn & Suites Sikeston, MO
Property amenity
Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, 1,009 reviews
"It was a perfect stay! Check in was friendly and efficient. The room was spotless. "
The price is $99
$112 total
includes taxes & fees
Jun 16 - Jun 17
Drury Inn & Suites Sikeston, MO
Travel Inn & Suites
Hallway
Travel Inn & Suites
2.5 star property
8.4 out of 10, Very Good, 527 reviews
"Very friendly check in staff. Room was comfortable. GREAT shower. "
The price is $60
$69 total
includes taxes & fees
Jun 17 - Jun 18
Travel Inn & Suites
Candlewood Suites Cape Girardeau, an IHG Hotel
Exterior
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 star property
8.2 out of 10, Very Good, 633 reviews
"Close to restaurants and the sports complex "
The price is $88
$104 total
includes taxes & fees
Jun 16 - Jun 17
Candlewood Suites Cape Girardeau, an IHG Hotel
Baymont by Wyndham Sullivan
Indoor pool, sun loungers
Baymont by Wyndham Sullivan
2.5 star property
7.8 out of 10, Good, 1,002 reviews
"It was good. We only stay for one night. It was very comfortable. We rest very well and continue to Route 66. "
The price is $98
$107 total
includes taxes & fees
Jun 30 - Jul 1
Baymont by Wyndham Sullivan
The Farmstead Hotel
Reception
The Farmstead Hotel
2.5 star property
8.8 out of 10, Excellent, 198 reviews
"The staff were wonderful. The room was nice and the bed was very comfortable. None of the charging outlets worked. The refrigerator freezer was unusable because it was filled with frost. Our bathroom mirror light strobed terribly and the toilet flushed 3 times for every flush. The hotel is new and lovely but is not in a nice part of town. If you're looking for a nice place to lay your head after exploring near by attractions it's great. But nearby restaurants are few and close fairly early, so...
The price is $103
$118 total
includes taxes & fees
Jul 10 - Jul 11
The Farmstead Hotel
Hampton Inn Cape Girardeau I 55 East
Courtyard
Hampton Inn Cape Girardeau I 55 East
2.5 star property
9.6 out of 10, Exceptional, 627 reviews
"I highly recommend staying here. "
The price is $114
$128 total
includes taxes & fees
Jun 16 - Jun 17
Hampton Inn Cape Girardeau I 55 East
Pear Tree Inn Sikeston
Lobby
Pear Tree Inn Sikeston
2.5 star property
9.4 out of 10, Exceptional, 1,010 reviews
"The front desk was really nice. My room had a roach in it and she moved me."
The price is $94
$108 total
includes taxes & fees
Jun 16 - Jun 17
Pear Tree Inn Sikeston
Super 8 by Wyndham Farmington
Exterior
Super 8 by Wyndham Farmington
2.0 star property
8.0 out of 10, Very Good, 436 reviews
"Good it had semi parking "
The price is $57
$65 total
includes taxes & fees
Jun 10 - Jun 11
Super 8 by Wyndham Farmington
Quality Inn
Lobby
Quality Inn
2.5 star property
7.0 out of 10, Good, 471 reviews
"Good location "
The price is $68
$77 total
includes taxes & fees
Jun 10 - Jun 11
Quality Inn
Best Western Plus Sikeston
Free daily full breakfast
Best Western Plus Sikeston
2.5 star property
8.4 out of 10, Very Good, 1,011 reviews
"Nice big room and was close to the freeway"
The price is $98
$111 total
includes taxes & fees
Jun 10 - Jun 11
Best Western Plus Sikeston
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More cheap stays in Southeast Missouri

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr, Sikeston, MO
The price is $69 per night from Jun 16 to Jun 17
$69
$78 total
includes taxes & fees
Jun 16 - Jun 17
7/10 Good! (1,008 reviews)

Stay near popular Southeast Missouri attractions

Image for Meramec Caverns

Meramec Caverns

5/5(21 reviews)

Explore the great outdoors at Meramec Caverns, a lovely green space in Sullivan. While in this family-friendly area, you can enjoy the coffeehouses.

See properties
Meramec Caverns

Recent reviews of Southeast Missouri hotels
Expedia verified reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

5/5 Excellent
"It was a perfect stay! Check in was friendly and efficient. The room was spotless. "
A verified traveler stayed at Drury Inn & Suites Sikeston, MO
Posted 12 hours ago
Drury Inn & Suites Sikeston, MO