Downtown South San Francisco, CA

San Francisco
Photo by Catherine Edejer-McCormick

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Downtown South San Francisco Hotel Deals

La Quinta Inn & Suites by Wyndham San Francisco Airport N
La Quinta Inn & Suites by Wyndham San Francisco Airport N
2.5 out of 5
20 Airport Blvd, South San Francisco, CA
The price is $110 per night from Jun 23 to Jun 24
$110
$129 total
includes taxes & fees
Jun 23 - Jun 24
Book a stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast ...
7.8/10 Good! (1,912 reviews)
"This is a great place to stay. It is close to the airport. There is a Denny's restaurant on site. We have stayed here frequently at the beginning or ending of a trip."

Reviewed on May 22, 2024

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Holiday Inn Golden Gateway, an IHG Hotel
Holiday Inn Golden Gateway, an IHG Hotel
3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
The price is $130 per night from Jun 16 to Jun 17
$130
$152 total
includes taxes & fees
Jun 16 - Jun 17
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the pool ...
8.6/10 Excellent! (2,552 reviews)
"Property was clean and modern. Conveniently located. Many restaurants and bars."

Reviewed on May 23, 2024

Holiday Inn Golden Gateway, an IHG Hotel
Handlery Union Square Hotel
Handlery Union Square Hotel
3.5 out of 5
351 Geary St, San Francisco, CA
The price is $139 per night from May 27 to May 28
$139
$162 total
includes taxes & fees
May 27 - May 28
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.6/10 Excellent! (1,872 reviews)
Wonderful first time experience at the Handlery.
"The shower -tub, did NOT drain well....water built up to have standing water. Also, I wanted to take a quick wash up with only having the tub water, the shower head drippled water on my hair. This was the only negative Also wish there had been instructions for using the TV remote. I had to call for ..."

Reviewed on May 20, 2024

Handlery Union Square Hotel
Hotel Riu Plaza Fisherman's Wharf
Hotel Riu Plaza Fisherman's Wharf
4 out of 5
2500 Mason St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is $135 per night from May 31 to Jun 1
$135
$191 total
includes taxes & fees
May 31 - Jun 1
Book a stay at this eco-certified hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.6/10 Excellent! (6,165 reviews)
"Hotel was in great location, clean and loved the breakfast buffet"

Reviewed on May 20, 2024

Hotel Riu Plaza Fisherman's Wharf
The Westin San Francisco Airport
The Westin San Francisco Airport
4 out of 5
1 Old Bayshore Hwy, Millbrae, CA
The price is $122 per night from May 27 to May 28
$122
$142 total
includes taxes & fees
May 27 - May 28
Book a stay at this business-friendly hotel in Millbrae. Enjoy breakfast (surcharge), a free airport shuttle, and a 24-hour fitness center. Our guests praise ...
8.6/10 Excellent! (1,980 reviews)
"This property is impeccably clean and beautiful! The staff are just as wonderful and so helpful! Special Kudos to Lily at the Front Desk for the swift check in and helping us on our last day. You rock! Thank you to Danny who waited on us at the restaurant. You are a wonderful server!"

Reviewed on May 22, 2024

The Westin San Francisco Airport
Club Quarters Hotel in San Francisco
Club Quarters Hotel in San Francisco
4 out of 5
424 Clay St, San Francisco, CA
The price is $127 per night from May 26 to May 27
$127
$148 total
includes taxes & fees
May 26 - May 27
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and ...
8.6/10 Excellent! (1,593 reviews)
"I was impressed with how comfortable the befs were and the location of the hotel which is close to everything. The housekeepers did a great job at making sure my room was cleaned daily with fresh sheets and towels."

Reviewed on May 23, 2024

Club Quarters Hotel in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Downtown South San Francisco

Mission District which includes outdoor art

Mission District

3.5/5(140 area reviews)

Mission District is a destination travelers like for its bars, and you might hop aboard the metro at 16th Street Mission Station or 24th Street Mission Station to explore sights like Mission Dolores Park.

Mission District
Castro District featuring street scenes

Castro District

4.5/5(48 area reviews)

Castro District is a destination travelers like for its bars, and you might hop aboard the metro at 17th St & Castro St Stop or Castro Station to explore sights like Castro Street.

Castro District
Anchor Brewing Company featuring a city

Potrero Hill

The live music and architecture are just a few things visitors like about Potrero Hill. San Francisco Bay and Letterform Archive are worthwhile spots to check out, and you can hop on the metro at 20th Street Station or 23rd Street Station to get around the larger area.

Potrero Hill
Sunset District which includes a bridge and a river or creek

Sunset District

3.5/5(172 area reviews)

Travelers choose Sunset District for its pristine beaches. Hop aboard the metro at Judah Street & Sunset Boulevard Station or Judah St & 34th Ave Stop and check out top sights like Golden Gate Park.

Sunset District
South of Market featuring skyline, a city and city views

South of Market

3.5/5(3,655 area reviews)

Oracle Park and Chase Center are top sights in South of Market, and you should be sure to explore the popular shops. Hop aboard the metro at Yerba Buena-Moscone Station or Fourth-Brannan Station to see more sights in the area.

South of Market
California Academy of Sciences which includes interior views as well as a large group of people

Golden Gate

While you're in Golden Gate, take in top sights like Golden Gate Park or San Francisco Botanical Garden, and hop on the metro to see more the city at Irving St & 9th Ave Stop or Irving St & 8th Ave Stop.

Golden Gate

Downtown South San Francisco, CA

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