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Compare hotels near Cairo Regional airport with room rates, reviews, and updated availability. Most hotels are fully refundable.

Quality Inn Cairo I-57
Exterior
Quality Inn Cairo I-57
2.5 star property
6.6 out of 10, 224 reviews
"Good bang for your buck! Price through the app was on point and $25 less than going through the hotel..Room was clean zero complaints on cleanliness except for the carpet that you could feel moisture in which also made the hallway and rooms smell..Get rid of the carpet and put down laminate and I’m pretty sure the smell would go away! "
The price is $75
$83 total
includes taxes & fees
Jun 6 - Jun 7
Quality Inn Cairo I-57
Cozy cabins on beautiful Horseshoe Lake
Interior
Cozy cabins on beautiful Horseshoe Lake
9.8 out of 10, Exceptional, 18 reviews
"We were looking for a place to view the 2024 solar eclipse and we found this cabin, which was in the path of totality! We were so excited to be able to view the eclipse from the property, which meant that we didn't have to deal with traffic getting home or to other lodging. Sherry was a great host. The cabin was quiet and clean. and just perfect for a two-night stay. "
The price is $115
$135 total
includes taxes & fees
Jun 6 - Jun 7
Cozy cabins on beautiful Horseshoe Lake
The Rested Duck Mallard Room
Dining
The Rested Duck Mallard Room
8.8 out of 10, Excellent, 15 reviews
"Quiet went fishing enjoyable only thing was the service "
The price is $115
$143 total
includes taxes & fees
Jun 6 - Jun 7
The Rested Duck Mallard Room
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Super 8 by Wyndham Charleston/Sikeston East MO
Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
6.8 out of 10, 501 reviews
"It was fine, nothing exceptional"
The price is $63
$70 total
includes taxes & fees
Jun 18 - Jun 19
Super 8 by Wyndham Charleston/Sikeston East MO
Eagle Inn Charleston
Desk, iron/ironing board, free WiFi, alarm clocks
Eagle Inn Charleston
2.0 star property
6.8 out of 10, 93 reviews
"Rooms dirty, full of flying bugs, walls dirty"
The price is $70
$78 total
includes taxes & fees
Jun 6 - Jun 7
Eagle Inn Charleston
Quality Inn - Sikeston
Desk, laptop workspace, blackout drapes, iron/ironing board
Quality Inn - Sikeston
2.5 star property
6.8 out of 10, 326 reviews
"no food"
The price is $63
$70 total
includes taxes & fees
Jun 17 - Jun 18
Quality Inn - Sikeston
La Center Motel
Basic Double Room | Free WiFi
La Center Motel
2.0 star property
6.0 out of 10, 3 reviews
"Very good. It’s an older motel but the new owners are repairing and upgrading units. Staff was willing to assist in any way, eager to please. Highly recommend."
The price is $57
$67 total
includes taxes & fees
Jun 6 - Jun 7
La Center Motel
Solar Eclipse Festival at our Campground at Benton Speedway. April 6-8th 2024.
Soap, toilet paper
Solar Eclipse Festival at our Campground at Benton Speedway. April 6-8th 2024.
The price is $40
$60 total
includes taxes & fees
Jun 6 - Jun 7
Solar Eclipse Festival at our Campground at Benton Speedway. April 6-8th 2024.
Solar Eclipse Festival Campground at Benton Speedway. April 6-8th 2024.
Interior
Solar Eclipse Festival Campground at Benton Speedway. April 6-8th 2024.
10.0 out of 10, Exceptional, 1 review
"As described. Happy with the experience for the eclipse."
Solar Eclipse Festival Campground at Benton Speedway. April 6-8th 2024.
Days Inn and Suites by Wyndham Sikeston
1 bedroom, desk, laptop workspace, blackout drapes
Days Inn and Suites by Wyndham Sikeston
2.0 star property
7.0 out of 10, Good, 1,009 reviews
"We only needed a room while passing thru. It was perfect. Staff was great, room was clean. We had no issues whatsoever. We will be staying here again."
The price is $68
$77 total
includes taxes & fees
Jun 6 - Jun 7
Days Inn and Suites by Wyndham Sikeston
Drury Inn & Suites Sikeston, MO
Property amenity
Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, 1,006 reviews
"Just made a quick stop late at night to get sleep and left too early for breakfast. Staff was very friendly and efficient. Bed was wonderful."
The price is $99
$112 total
includes taxes & fees
Jun 16 - Jun 17
Drury Inn & Suites Sikeston, MO
Beautiful Cabin Retreat
Beautiful Cabin Retreat
8.2 out of 10, Very Good, 39 reviews
"Host had the cabin very clean. New leather couch & recliner. Mattress was extremely comfortable. Washer & Dryer were excellent. Another Rental house near, long-term renters were very quiet. Internet not very good in the Illinois woods. Closed cabin has a musty smell from humidity in the woods. Host had an automatic air freshener going to help with air quality."
The price is $120
$193 total
includes taxes & fees
Jun 6 - Jun 7
Beautiful Cabin Retreat
Pear Tree Inn Sikeston
Lobby
Pear Tree Inn Sikeston
2.5 star property
9.4 out of 10, Exceptional, 1,008 reviews
"Very clean"
The price is $94
$108 total
includes taxes & fees
Jun 10 - Jun 11
Pear Tree Inn Sikeston
Best Western Plus Sikeston
Free daily full breakfast
Best Western Plus Sikeston
2.5 star property
8.4 out of 10, Very Good, 1,008 reviews
"Limited parking for RV or trucks."
The price is $98
$111 total
includes taxes & fees
Jun 9 - Jun 10
Best Western Plus Sikeston
Travel Inn & Suites
Hallway
Travel Inn & Suites
2.5 star property
8.4 out of 10, Very Good, 527 reviews
"Very friendly check in staff. Room was comfortable. GREAT shower. "
The price is $60
$69 total
includes taxes & fees
Jun 13 - Jun 14
Travel Inn & Suites
Country Yard Inn and Suite
Iron/ironing board, free WiFi, bed sheets
Country Yard Inn and Suite
2.0 star property
7.4 out of 10, Good, 34 reviews
"Considering the price of the room, it was adequate. Thankfully it was a cooler weekend (the previous week had been uncharacteristically warm) or we would have had to move rooms due to an inadequate air conditioning unit. That being said, it was a clean room and the bed was comfortable. The motel is convenient to the interstate and the main road into Sikeston. Our room was at the far end of the motel, so away from any interstate noise."
The price is $61
$72 total
includes taxes & fees
Jun 30 - Jul 1
Country Yard Inn and Suite
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
Exterior
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
10.0 out of 10, Exceptional, 140 reviews
"Quaint red home near horse farm is exactly as the description in the post describes the property in an excellent manner. My children enjoyed having separate rooms and we were able to cook a full dinner and breakfast both days. If we ever go back we will surely keep this rental in mind."
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
Comfort Inn & Suites Sikeston I-55
Exterior
Comfort Inn & Suites Sikeston I-55
2.5 star property
8.4 out of 10, Very Good, 199 reviews
"Seems like clean well kept property!"
The price is $92
$105 total
includes taxes & fees
Jun 9 - Jun 10
Comfort Inn & Suites Sikeston I-55
Charming cottage overlooking Lake Acre
Exterior
Charming cottage overlooking Lake Acre
10.0 out of 10, Exceptional, 84 reviews
"What a cute property that is nicely furnished and very comfortable. Suzie was a great host and we’d definitely book this place again."
The price is $150
$256 total
includes taxes & fees
Jun 6 - Jun 7
Charming cottage overlooking Lake Acre
Super 8 by Wyndham Sikeston/Miner Area
Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout drapes, free cribs/infant beds
Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
6.4 out of 10, 475 reviews
"Nice quiet place no noise "
The price is $60
$68 total
includes taxes & fees
Jun 12 - Jun 13
Super 8 by Wyndham Sikeston/Miner Area
Don't see what you're looking for?
See all available properties in Cairo, IL (CIR-Cairo Regional)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's the area like near Cairo, IL (CIR-Cairo Regional)?

If you're flying into Cairo, IL (CIR-Cairo Regional), you might take some time to enjoy the sights in town. If you're looking for a convenient place to stay, you might search for properties close to public transportation so it's easy to get around.

What's the best place to stay near Cairo, IL (CIR-Cairo Regional)?

Quality Inn Cairo I-57 is one of the top choices for your stay and is a popular hotel, featuring free breakfast and free WiFi. It's located 2.1 mi (3.3 km) from Cairo, IL (CIR-Cairo Regional).

Recent reviews of Cairo Regional hotels
Expedia verified reviews

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

5/5 Excellent
"We only needed a room while passing thru. It was perfect. Staff was great, room was clean. We had no issues whatsoever. We will be staying here again."
A verified traveler stayed at Days Inn and Suites by Wyndham Sikeston
Posted 1 day ago
Days Inn and Suites by Wyndham Sikeston