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Find 5 Star Hotels in Medical Center District, TX from $119

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Compare Medical Center District 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Outdoor pool, open 7:00 AM to 10:00 PM, cabanas (surcharge)
Thompson San Antonio - Riverwalk, by Hyatt
5.0 star property
8.8 out of 10, Excellent, (495)
"Lo que no me gusto fue su servicio con expedia ya que se tarda en reflejarse el pago al hotel y por esa razon no nos dejaron hospedarnos, el hotel esta espectacular sin ninguna queja. Ustedes como intermediarios son el problema "
The price is $254
$305 total
includes taxes & fees
Jun 16 - Jun 17
Thompson San Antonio - Riverwalk, by Hyatt
Outdoor pool
The Luxury Suites at Arrive Eilan
5.0 star property
7.4 out of 10, Good, (129)
"Very nice. Easy and Clean"
The Luxury Suites at Arrive Eilan

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Medical Center District.
Riverwalk Plaza

Riverwalk Plaza

100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
The price is $119 per night from Jun 2 to Jun 3
$119
$141 total
includes taxes & fees
Jun 2 - Jun 3
8/10 Very Good! (3,581 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Medical Center District?
The amount you pay for a 5-star hotel in Medical Center District depends on factors such as when you plan to travel and the length of your vacation. An insider tip for bagging the best deal? Use our pricing filters to check out all of the available options for your chosen dates.

  • Search for the lowest price per night from $119

What makes a hotel 5 stars in Medical Center District?
From high-end restaurants and all-day gyms to pools and luxury bedding, the 5-star experience in Medical Center District is all about relaxation and luxury. But it requires more than just upscale amenities to receive a 5-star rating. Stays must also offer superb guest-focused services like in-room massages, dry cleaning and laundry and concierge services.
Are there any 5-star all-inclusive resorts in Medical Center District?
Find an upscale getaway that includes your room, meals, activities and entertainment in Medical Center District with our handy filter tool. Search for hotels rated 5 stars and click on the “All inclusive” filter. Have a look at what’s included in the upfront price. This way, you’ll be ready to maximize the premium perks on offer when you arrive.
Are there any 5-star vacation rentals in Medical Center District?
There are no 5-star vacation rentals in Medical Center District on our site, but there are a few other highly rated properties worth checking out. Search through our vacation rentals in Medical Center District to discover the ideal place for your getaway.